Do “gobernar es poblar” ao “educar es argentinizar”

Beethoven (Muss es sein? Es muss sein!)

"The child is father of the man" is the philosophy of the paediatrician, hence the recent trend of intense interest in child development, which embraces the study of factors which influence the growth of the body, mind, personality and spirit from conception to maturity and ultimate achievement. As practitioners of medicine it is natural that much of our effort should be used in the diagnosis a...

Upwinding Sour es at Interfa es in onservation laws

iPS and ES Cells: Do Both Roads Lead to Rome?

The seminal report from Takahashi and Yamanka in 2006 describing the reprogramming of somatic cells to induced pluripotent stem (iPS) cells [1] marked the beginning of a new field of research, resulting in hundreds of publications in a short 3 years. Among other things, the promise of iPS cells in cell therapy circumvents many of the ethical concerns associated with embryonic stem (ES) cell res...

Reanalyzing German Correlative Es

Several Germanic languages use correlatives to mark subordination. German is considered to be a prime example of a language realizing correlative constructions to embed finite argument clauses. This paper discusses complex clausal constructions in German that can be identified by a so-called correlative nominal element es (‘it’) and a right-peripheral full clausal argument that is linked to es....

ES cells without teratomas

Transport if loaded uclear transporters can be viewed as taxis that move cargo across the nuclear envelope. On page 649, Plafker et al. report that importin-11, a nuclear transport receptor , may be an especially selective cabbie. Importin-11 transports UbcM2, a ubiquitin (Ub)-conjugating enzyme, but it does so only when the enzyme is charged with a Ub at its active site. UbcM2 is an E2 enzyme,...